Saliva test may turn tide on prostate cancer claim scientists

A salivary test can “bear the tide” on prostate cancer “, claims the UK scientists.

It analyzes men’s DNA, which was born with the greatest risk of developing the disease.

Targeting them for prostate biopsy and MRI scans, discovered some aggressive cancer that would have gone otherwise.

However, the test has not yet been proven to save life and experts say that it will be “year” before such tests are used regularly.

Around 12,000 men in the UK die of prostate cancer every year.

Call for regular testing of healthy men – known as screening – Olympic cyclist Sir Chris Hoy announced that he had a terminal prostate cancer.

The screening has been rejected in the past because using the current test – which seeks the levels of the prostate specific antigen (PSA) in the blood – Risk causes more harm than good,

This saliva test does not seek signs of prostate cancer inside the body.

Instead it seeks 130 mutations in men’s DNA, each of which can increase the risk of development of prostate cancer.

In the study, scientists tested men at the age of 55–69 and calculated their risk. In the top 10% score, men were invited for further investigation. It included a biopsy and an MRI scan.

The study published in New England Journal of Medicine showed:

• Of the 745 men with high score, 468 were ready to test additional additional tests
• Prostate cancer found on 187
• There were 103 high -risk tumors requiring treatment, 74 of these would not have been discovered at this level with current tests.

“With this test, it may be possible to turn the tide on prostate cancer,” said Ros Eles, Professor Ros Eles of the Institute of Cancer Research, London.

“We can identify men at the risk of aggressive cancer, who need further tests and leave men who are at risk from unnecessary treatments,” she said

Dhiresh Turnbull, who is 71 years old and from Brighton, attended the test.

He found that despite having no family history of prostate cancer, he was in the highest risk category. Further examination revealed that he had cancer.

“I was completely surprised, if I did not appear in the test, I never came to know at this level.”

His younger brother was then invited to participate in the study and also revealed that he had an aggressive tumor.

“It is incredible to think that this study has now saved the lives of two people in my family,” Dhiresh said.

However, the test is not ready to roll out.

Professor Dosco Iik of King’s College London said it was “promising”, but improves cancer detection “only” marginally “when used with existing risk factors such as age, PSA level and MRI scans.

And he said that there was still no direct evidence to survive or improve the quality of life, which meant that more study was required.

Research also focused people from the European dynasty and the work is still running to customize it for other background people. Black men are thought about The risk of prostate cancer doubles,

The research team also says that cost-efficiency, potential loss and risk are the best time to analyze.

Saliva will become part of the test Decisive conversion test Which is trying to find the best way to start screening prostate cancer in the UK.

Professor Michael Innao of Cambridge University said that he believes that we would look back as “a landmark” on this study, which made a case to use genetics to assess the risk.

But he said: “This is a big step along the path of clinical implementation, but it is still a long road.”

He said that NHS “this would be the possibility of the year” before using such tests.

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