Living tissues may form like avalanches, a discovery that could aid new treatments

An avalanche is caused by a series of events. A vibration or change in terrain can have a cascading and disastrous effects.

A similar process can occur when living tissues are subject to push or stretching, according to it New research published in Nature communicationSupervision was done by Doctor Anh Nguyen of Northeast University and Northeastern Physics Professor Max B.

As theoretical physicists, BIs and Guyen use computational modeling and mathematics to understand mechanical processes passing through organisms at a cellular level. With this more recent work, he has seen that when subject to enough stress, tissue can “suddenly and dramatically regain themselves,” how the avalanche is formed in the wild.

This observation challenges the notion that mechanical reactions in tissues are perfectly localized, instead suggests that stress redistribution can lead to coordinated re -conditions in large areas, BI explains.

“What ANH has found in these computational simulations is that these (cells) are actually mechanically talking, which means that if the rearring is with four cells, the energy issued from these four cells is sufficient to go through re -condition to other cells.”

Biologically, this discovery can help engineering in new types of tissues, skin grafting or other wound healing research. In understanding this mechanical process, researchers may also have a better understanding of how to trigger or prevent it from being in the first place.

“How do we prevent avalanche from happening if we want or conversely, how do we allow avalanche to be more easily?” He says.

He points to this discovery ability to be used for cancer research. When the cancer metastezes, the cells in the body go to the highwear and start flowing in parts of the body, which they should not have, call BIs.

“If we can find physical principles that catch these cells back, prevent them from rearring – oral – it can be a guiding theory to keep cancer back. It is a dream. It is a dream. What are the physical ways to keep cancer, to keep it?”

This is also just an attractive discovery because physicists are always looking for universal behavior among unequal systems.

“It is looking for a physicist’s dream for universality,” says BE.

These insights are currently based in computational modeling. The two and the Gujarin are collaborating with the biologist to find out whether the same mechanical behavior can be seen in living tissues.

“We are actively collaborating with experiments to observe this behavior in biological tissues,” BE says. “Given the universality we see in the mobility of avalanche, from the earthquake to the flow of plastic in the soft material, I strongly believe that similar collective resurrection should be present in the tissues as well. Physics does not depend on whether the system is made of cells or sand.”

This story has been reinstated courtesy of Northeastern Global News News.northeastern.edu,