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Cinnamon may be a beloved spice in kitchens and health stores alike, but a new study has found that overconsumption could interfere with how the body processes prescription drugs.
Published in the journal Food Chemistry: Molecular Sciences, the study found that cinnamaldehyde – the active compound in cinnamon – is highly bioaccessible and may interact with enzymes that affect drug metabolism.
The findings suggest that excessive intake of cinnamon-containing supplements or products could result in herb-drug interactions, particularly for individuals taking medications or managing chronic conditions.
“Cinnamon is not harmless just because it’s natural,” said Dr Leana Wen, a health policy expert and physician. “People need to understand its potential risks, especially if they are on prescription drugs.”
Cinnamon, especially the Cassia variety commonly sold in North America, contains high levels of coumarin – a naturally occurring compound known to thin blood.
In large quantities, this could increase the risk of bleeding, particularly in individuals already on anticoagulant medication.
The National Center for Complementary and Integrative Health (NCCIH) has stated that research does not currently support the use of cinnamon for any specific health condition, and the US Food and Drug Administration has not approved cinnamon as a treatment.
While Ceylon cinnamon, often marketed as “true” cinnamon, contains less coumarin, it too may pose risks if consumed in large amounts over time.
Liver damage and possible interference with anti-cancer drugs or nicotine are among the potential issues raised.
The study’s authors called for further research to determine the extent of drug interactions and recommended that individuals consult healthcare professionals before taking cinnamon supplements.
Despite some early studies suggesting benefits for weight loss or managing diabetes, experts caution against relying on cinnamon as a therapeutic aid without clear clinical evidence.
